THE BENEFITS OF CELLEX™ TECHNOLOGY ADVANCING KNOWLEDGE ON ECP TECHNOLOGY Mar 2026

The Goal

The goal of this practical course is to provide state of the art guidance, tips and best practices on theuse of the THERAKOS™ CELLEX™ Photopheresis System. The interactive setting allows exchanges and fosters discussion between peers.

Agenda

Download Agenda PDF

Day 1 - 4 March 2026

Arrival of participants

19.00 – 19.30
Meeting in the lobby

19.30
Dinner

Day 2 - 4 March 2026

08.00 – 08.30
Introduction - Prof. Mirjana Ziemer, Jan Simon and Therakos International Healthcare Stakeholders Engagement Department

08.30 – 09.15
Benefits of THERAKOS™ CELLEX™ Photopheresis System - Clinical Service Therakos

09.15 – 09.45
Venous Access, Best Practices - Prof. Mirjana Ziemer

09.45 – 10.00
Buffy Coat – Group 1 - Clinical Service Therakos

Anticoagulants in ECP – Group 2 - Leipzig team

10.00 – 10.15
Patient Treatment, Use of DNM/SNM and ECV Management - Leipzig team

10.15 – 10.30
Coffee Break

10.30 – 11.30
Bowl Optic Sensor and Alarm Resolution - Clinical Service Therakos

11.30 – 12.15
Moving toward Excellence in Efficiency - Leipzig team

12.15 – 12.30
Anticoagulants in ECP – Group 1

12.15 – 12.30
Buffy Coat – Group 2 - Clinical Service Therakos

12.30 – 13.15
Lunch

13.15 – 14.30
Patient Treatment and Troubleshooting Hints - Leipzig team

DNM: Double Needle Mode, ECP: Extracorporeal Photopheresis, ECV: Extracorporeal Volume, SNM: Single Needle Mode

Please see the THERAKOS™ CELLEX™ Photopheresis System operator’s Manual for indications,contraindications, warnings, precautions, adverse reactions, and other important information.

All speakers are subject to contract.
This is a commercial programme run by Therakos (UK) Ltd
This information is intended for healthcare professionals based in Europe and the Middle East.

Hosted by

Prof. Mirjana Ziemer

Director of Extracorporeal Photopheresis, University of Leipzig Medical Center, Department of Dermatology, Allergology and Venereology

Prof. Jan C. Simon

Clinical Director, University of Leipzig Medical Center, Department of Dermatology, Allergology and Venereology

Brought to you by the Therakos Institute

This is a commercial programme run by Therakos (UK) Ltd.

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IMPORTANT SAFETY INFORMATION FOR THE THERAKOS™ PHOTOPHERESIS PROCEDURE

Indications

The THERAKOS™ CELLEX™ Photopheresis System is indicated for patients older than 18 years of age for the administration of photopheresis in the following:

Cutaneous T Cell Lymphoma (CTCL)
Solid Organ Transplant Rejection (SOT) (heart, lung)

The THERAKOS™ CELLEX™ Photopheresis System is indicated in patients older than 3 years of age for the management of:

Acute and Chronic Graft versus Host Disease (aGvHD, cGvHD)

Contraindications

THERAKOS^TM Photopheresis is contraindicated in:

Patients possessing a specific history of a light sensitive disease
Patients who cannot tolerate extracorporeal volume loss or who have white blood cell counts greater than 25,000 / mm³
Patients who have coagulation disorders or who have previously had a splenectomy

Warnings and Precautions

THERAKOS^TMPhotopheresis treatments should always be performed in locations where standard medical emergency equipment is available. Volume replacement fluids and/or volume expanders should be readily available throughout the procedure.

Do not expose the device to a magnetic resonance (MR) environment. The device may present a risk of projectile injury, and thermal injury and burns may occur. The device may generate artifacts in the MR image, or may not function properly.
Thromboembolic events, including pulmonary embolism and deep vein thrombosis, have been reported in the treatment of Graft versus Host Disease (GvHD). Special attention to adequate anticoagulation is advised when treating patients with GvHD.
When prescribing and administering THERAKOS Photopheresis for patients receiving concomitant therapy, exercise caution when changing treatment schedules to avoid increased disease activity that may be caused by abrupt withdrawal of previous therapy.

Adverse Events

Hypotension may occur during any treatment involving extracorporeal circulation. Closely monitor the patient during the entire treatment for hypotension.
Transient pyretic reactions, 37.7–38.9°C (100–102°F), have been observed in some patients within six to eight hours of reinfusion of the photoactivated leukocyte-enriched blood. A temporary increase in erythroderma may accompany the pyretic reaction.
Treatment frequency exceeding labelling recommendations may result in anaemia.
Venous access carries a small risk of infection and pain.

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOS^TM PHOTOPHERESIS

Consult the 8-methoxypsoralen (Methoxsalen (20 micrograms / mL)) professional leaflet or the oral 8-methoxypsoralen formulation package insert before prescribing or dispensing any medication.

Warnings and Precautions

Patients exhibiting multiple basal cell carcinomas or having a history of basal cell carcinoma should be diligently observed and treated.
Methoxsalen may cause fetal harm when given to a pregnant woman. Women undergoing photopheresis should be advised to avoid becoming pregnant.
Special care should be exercised in treating patients who are receiving concomitant therapy (either topically or systemically) with known photosensitizing agents.
Oral administration of methoxsalen followed by cutaneous UVA exposure (PUVA therapy) is carcinogenic.
Patients should be told emphatically to wear UVA absorbing, wrap-around sunglasses for twenty-four (24) hours after methoxsalen treatment. They should wear these glasses any time they are exposed to direct or indirect sunlight, whether they are outdoors or exposed through a window.

Refer to the package insert for methoxsalen sterile solution (20 micrograms / mL) or the oral 8-methoxypsoralen dosage formulation for a list of all warnings and precautions.

The Benefits of CELLEX™ Technology - Advancing Knowledge on ECP Technology

The Goal

Agenda

Day 1 - 4 March 2026

Day 2 - 4 March 2026

Hosted by

Brought to you by the Therakos Institute

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THERAKOS™ CELLEX™ Photopheresis System - Advancing Knowledge on ECP Technology

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