Educational Course on CTCL

The Goal

The goal of the dermatology interactive course is to provide the latest views on the use of Extracorporeal Photopheresis in CTCL and foster discussion between peers.

Agenda

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Day 1 - 11 November 2026

Arrival of participants

19.00 – 19.30
Meeting in the lobby

19.15
Dinner

Day 2 - 12 October 2026

08:30 – 08:45
Welcome and introduction - Prof Chalid Assaf & Therakos Healthcare Stakeholder Engagement Department

08:45 – 09:00
Current and new challenges in the diagnosis and management of CTCL - Prof Chalid Assaf

09:00 – 09:30
CTCL clinical and molecular features - Prof Constanze Jonak

19.30 – 10.00
Where does Extracorporeal Photopheresis belong in the management of CTCL? - Prof Chalid Assaf

10:00 – 10:15
Interactive Discussion - All

10:15 – 10:30
Coffee Break

10:30 – 11:00
ECP Mechanism of Action: novel perspectives - Prof Emmanuella Guenova

11:00 – 11:30
ECP as combination partner: potential synergies and molecular effects - Prof Jan Nicolay

11:30 – 12:30
Interactive discussion and CTCL case reports shared by the Faculty

Complex clinical cases on CTCL manifestations - Prof Gabor Dobos, Prof Emmanuella Guenova, Prof Costanze Jonak, Prof Jan Nicolay

12:30 – 13:30
Lunch

13:30 – 14:00
Practical recommendations for the therapy of CTCL patients - Prof Gabor Dobos

14:00 – 14:15
Peer to peer forum - Prof Chalid Assaf, Prof Gabor Dobos, Prof Emmanuella Guenova, Prof Costanze Jonak, Prof Jan Nicolay

14:15 – 14:30
Coffee break

14:30 – 15:30
Interactive discussion and patient cases shared by HCPs attendees - All

15:30 – 15:45
Final remarks and close - Prof Chalid Assaf

CTCL: Cutaneous T-Cell Lymphoma, ECP: Extracorporeal Photopheresis, HCP: Healthcare practitioner

For this course, participants are required to submit one patient case for discussion 15 days in advance of the session.

All speakers are subject to contract.
This is a commercial programme run by Therakos (UK) Ltd
This information is intended for healthcare professionals based in Europe and the Middle East.

Our Centres of Excellence (CoE) Programme is for customers only. If you are interested in attending our CoE courses please contact your Sales Representative.

IMPORTANT SAFETY INFORMATION FOR THE THERAKOS™ PHOTOPHERESIS PROCEDURE

Indications

The THERAKOS™ CELLEX™ Photopheresis System is indicated for patients older than 18 years of age for the administration of photopheresis in the following:

Cutaneous T Cell Lymphoma (CTCL)
Solid Organ Transplant Rejection (SOT) (heart, lung)
Treatment of immune related adverse events (irAE’s) associated with Immune checkpoint inhibitor (ICI) therapy in patients with inadequate response to corticosteroids

The THERAKOS™ CELLEX™ Photopheresis System is indicated in patients older than 3 years of age for the management of:

Acute and Chronic Graft versus Host Disease (aGvHD, cGvHD)

Contraindications

THERAKOS^TM Photopheresis is contraindicated in:

Patients possessing a specific history of a light sensitive disease
Patients who cannot tolerate extracorporeal volume loss or who have white blood cell counts greater than 25,000 / mm³
Patients who have coagulation disorders or who have previously had a splenectomy

Warnings and Precautions

THERAKOS^TMPhotopheresis treatments should always be performed in locations where standard medical emergency equipment is available. Volume replacement fluids and/or volume expanders should be readily available throughout the procedure.

Do not expose the device to a magnetic resonance (MR) environment. The device may present a risk of projectile injury, and thermal injury and burns may occur. The device may generate artifacts in the MR image, or may not function properly.
Thromboembolic events, including pulmonary embolism and deep vein thrombosis, have been reported in the treatment of Graft versus Host Disease (GvHD). Special attention to adequate anticoagulation is advised when treating patients with GvHD.
When prescribing and administering THERAKOS Photopheresis for patients receiving concomitant therapy, exercise caution when changing treatment schedules to avoid increased disease activity that may be caused by abrupt withdrawal of previous therapy.

Adverse Events

Hypotension may occur during any treatment involving extracorporeal circulation. Closely monitor the patient during the entire treatment for hypotension.
Transient pyretic reactions, 37.7–38.9°C (100–102°F), have been observed in some patients within six to eight hours of reinfusion of the photoactivated leukocyte-enriched blood. A temporary increase in erythroderma may accompany the pyretic reaction.
Treatment frequency exceeding labelling recommendations may result in anaemia.
Venous access carries a small risk of infection and pain.

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOS^TM PHOTOPHERESIS

Consult the 8-methoxypsoralen (Methoxsalen (20 micrograms / mL)) professional leaflet or the oral 8-methoxypsoralen formulation package insert before prescribing or dispensing any medication.

Warnings and Precautions

Patients exhibiting multiple basal cell carcinomas or having a history of basal cell carcinoma should be diligently observed and treated.
Methoxsalen may cause fetal harm when given to a pregnant woman. Women undergoing photopheresis should be advised to avoid becoming pregnant.
Special care should be exercised in treating patients who are receiving concomitant therapy (either topically or systemically) with known photosensitizing agents.
Oral administration of methoxsalen followed by cutaneous UVA exposure (PUVA therapy) is carcinogenic.
Patients should be told emphatically to wear UVA absorbing, wrap-around sunglasses for twenty-four (24) hours after methoxsalen treatment. They should wear these glasses any time they are exposed to direct or indirect sunlight, whether they are outdoors or exposed through a window.

Refer to the package insert for methoxsalen sterile solution (20 micrograms / mL) or the oral 8-methoxypsoralen dosage formulation for a list of all warnings and precautions.

Educational Course on CTCL

The Goal

Agenda

Day 1 - 11 November 2026

Day 2 - 12 October 2026

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