EDUCATIONAL COURSE ON CTCL 2026

The Goal

The goal of the dermatology interactive course is to provide the latest views on the use of Extracorporeal Photopheresis (ECP) in Cutaneous T Cell Lymphoma (CTCL) and foster discussion between peers.

Agenda

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Day 1 - 25 February 2026

Arrival of participants

19.00 – 19.15
Meeting in the lobby

19.15
Dinner

Day 2 - 26 February 2026

08:30 – 08:45
Welcome and introduction - Prof Julia Scarisbrick & Therakos International Healthcare Stakeholder Engagement department

08:45 – 09:00
The “Then”: where did the journey begin? - Prof Julia Scarisbrick

09:00 – 09:30
The “Now”: CTCL and ECP – CTCL Pathophysiology - Prof Emmanuella Guenova

09:30 – 10:00
The “Now”: CTCL and ECP – ECP proposed Mechanism of Action in CTCL - Prof Emmanuella Guenova

10:00 – 10:15
Interactive Discussion - All

10:15 – 10:30
Coffee Break

10:30 – 11:00
ECP in CTCL: evidence, guidelines and TTNT as a novel tool to measure response - Prof Julia Scarisbrick

11:00 – 11:30
Skin GvHD - Prof Dr Hildegard Greinix

11:30 – 12:30
Interactive discussion and CTCL case reports shared by the Faculty - All

12:30 – 13:30
Lunch

13:30 – 14:00
The “Beyond”: Durability of response of ECP-based combination therapy in CTCL - Prof Jan Nicolay

14:00 – 14:15
Peer to peer forum - Prof Jan Nicolay and Prof Emmanuella Guenova

14:15 – 14:30
Coffee Break

14:30 – 15:30
Interactive discussion and patient cases shared by HCPs attendees - All

15:30 – 15:45
Final remarks and close - Prof Julia Scarisbrick

HCP. Healthcare practitioner TTNT. Time to Next Treatment ECP: Extracorporeal
Photopheresis CTCL:Cutaneous T-cell Lymphoma

For this course, participants are required to submit one patient case for discussion 15 days in
advance of the session

All speakers are subject to contract.
This is a commercial programme run by Therakos (UK) Ltd
This information is intended for healthcare professionals based in Europe.

Hosted by

Prof Julia Scarisbrick

Consultant Dermatologist at Queen Elizabeth Hospital, Birmingham and Honorary Professor at University of Birmingham. Chair of the EORTC Cutaneous Lymphoma Taskforce

Brought to you by the Therakos Institute

This is a commercial programme run by Therakos (UK) Ltd.

Our Centres of Excellence (CoE) Programme is for customers only. If you are interested in attending our CoE courses please contact your Sales Representative.

IMPORTANT SAFETY INFORMATION FOR THE THERAKOS™ PHOTOPHERESIS PROCEDURE

Indications

The THERAKOS™ CELLEX™ Photopheresis System is indicated for patients older than 18 years of age for the administration of photopheresis in the following:

Cutaneous T Cell Lymphoma (CTCL)
Solid Organ Transplant Rejection (SOT) (heart, lung)

The THERAKOS™ CELLEX™ Photopheresis System is indicated in patients older than 3 years of age for the management of:

Acute and Chronic Graft versus Host Disease (aGvHD, cGvHD)

Contraindications

THERAKOS^TM Photopheresis is contraindicated in:

Patients possessing a specific history of a light sensitive disease
Patients who cannot tolerate extracorporeal volume loss or who have white blood cell counts greater than 25,000 / mm³
Patients who have coagulation disorders or who have previously had a splenectomy

Warnings and Precautions

THERAKOS^TMPhotopheresis treatments should always be performed in locations where standard medical emergency equipment is available. Volume replacement fluids and/or volume expanders should be readily available throughout the procedure.

Do not expose the device to a magnetic resonance (MR) environment. The device may present a risk of projectile injury, and thermal injury and burns may occur. The device may generate artifacts in the MR image, or may not function properly.
Thromboembolic events, including pulmonary embolism and deep vein thrombosis, have been reported in the treatment of Graft versus Host Disease (GvHD). Special attention to adequate anticoagulation is advised when treating patients with GvHD.
When prescribing and administering THERAKOS Photopheresis for patients receiving concomitant therapy, exercise caution when changing treatment schedules to avoid increased disease activity that may be caused by abrupt withdrawal of previous therapy.

Adverse Events

Hypotension may occur during any treatment involving extracorporeal circulation. Closely monitor the patient during the entire treatment for hypotension.
Transient pyretic reactions, 37.7–38.9°C (100–102°F), have been observed in some patients within six to eight hours of reinfusion of the photoactivated leukocyte-enriched blood. A temporary increase in erythroderma may accompany the pyretic reaction.
Treatment frequency exceeding labelling recommendations may result in anaemia.
Venous access carries a small risk of infection and pain.

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOS^TM PHOTOPHERESIS

Consult the 8-methoxypsoralen (Methoxsalen (20 micrograms / mL)) professional leaflet or the oral 8-methoxypsoralen formulation package insert before prescribing or dispensing any medication.

Warnings and Precautions

Patients exhibiting multiple basal cell carcinomas or having a history of basal cell carcinoma should be diligently observed and treated.
Methoxsalen may cause fetal harm when given to a pregnant woman. Women undergoing photopheresis should be advised to avoid becoming pregnant.
Special care should be exercised in treating patients who are receiving concomitant therapy (either topically or systemically) with known photosensitizing agents.
Oral administration of methoxsalen followed by cutaneous UVA exposure (PUVA therapy) is carcinogenic.
Patients should be told emphatically to wear UVA absorbing, wrap-around sunglasses for twenty-four (24) hours after methoxsalen treatment. They should wear these glasses any time they are exposed to direct or indirect sunlight, whether they are outdoors or exposed through a window.

Refer to the package insert for methoxsalen sterile solution (20 micrograms / mL) or the oral 8-methoxypsoralen dosage formulation for a list of all warnings and precautions.

Educational Course on CTCL