Operators Day UK

17 September 2026

Birmingham, UK

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Time: 08:15 – 15:00

Moderator: Joanne Bird, University Hospitals Birmingham NHS Foundation Trust

08:15 – 08:25

Registration

08:25 – 08:30

Welcome & introduction

Joanne Bird, University Hospitals Birmingham NHS Foundation Trust

08:30 – 08:45

MDR approved indications for the THERAKOS™ CELLEX™ Photopheresis System

Therakos Medical Affairs

08:45 – 09:30

The missing piece – supportive care, patient reported outcomes, & what next?

Dr Francesca Kinsella, University Hospitals Birmingham NHS Foundation Trust

09:30 – 10:00

Body image and survivorship

Dr Helen Aiston, Southampton University Hospital

10:00 – 10:15

Q&A Supportive Care

10:15 – 10:30

Coffee

10:30 – 11:15

Patient’s considerations when receiving ECP – venous access in the difficult patient

Prof Nina Worel, Medical University of Vienna

11:15 – 11:30

Q&A Venous Access

11:30 – 12:00

Introduction to ACD-A with the THERAKOS™ CELLEX™ Photopheresis System and Correct Connect

Therakos Clinical Specialist Team

12:00 – 12:45

THERAKOS™ CELLEX™ Photopheresis System troubleshooting session

Therakos Clinical Specialist Team

12:45 – 13:30

Lunch

13:30 – 14:00

Kahoot interactive quiz – What have we learned

Therakos Clinical Specialist Team

14:00 – 15:00

THERAKOS™ CELLEX™ Photopheresis System – Sharing best practice

Therakos Clinical Specialist Team

15:00

Feedback survey, final remarks & close

Joanne Bird, University Hospitals Birmingham NHS Foundation Trust

Please see the THERAKOS™ CELLEX™ Photopheresis System operator’s Manual for indications, contraindications, warnings, precautions, adverse reactions, and other important information.

ABMR: Antibody-Mediated Rejection, CLAD: Chronic Lung Allograft Dysfunction, ECP: Extracorporeal Photopheresis, SOT: Solid Organ Transplantation

All speakers are subject to contract.

Brought to you by the Therakos Institute

This is a commercial programme run by Therakos (UK) Ltd.

IMPORTANT SAFETY INFORMATION FOR THE THERAKOS™ PHOTOPHERESIS PROCEDURE

Indications

The THERAKOS™ CELLEX™ Photopheresis System is indicated for patients older than 18 years of age for the administration of photopheresis in the following:

Cutaneous T Cell Lymphoma (CTCL)
Solid Organ Transplant Rejection (SOT) (heart, lung)

The THERAKOS™ CELLEX™ Photopheresis System is indicated in patients older than 3 years of age for the management of:

Acute and Chronic Graft versus Host Disease (aGvHD, cGvHD)

Contraindications

THERAKOS^TM Photopheresis is contraindicated in:

Patients possessing a specific history of a light sensitive disease
Patients who cannot tolerate extracorporeal volume loss or who have white blood cell counts greater than 25,000 / mm³
Patients who have coagulation disorders or who have previously had a splenectomy

Warnings and Precautions

THERAKOS^TMPhotopheresis treatments should always be performed in locations where standard medical emergency equipment is available. Volume replacement fluids and/or volume expanders should be readily available throughout the procedure.

Do not expose the device to a magnetic resonance (MR) environment. The device may present a risk of projectile injury, and thermal injury and burns may occur. The device may generate artifacts in the MR image, or may not function properly.
Thromboembolic events, including pulmonary embolism and deep vein thrombosis, have been reported in the treatment of Graft versus Host Disease (GvHD). Special attention to adequate anticoagulation is advised when treating patients with GvHD.
When prescribing and administering THERAKOS Photopheresis for patients receiving concomitant therapy, exercise caution when changing treatment schedules to avoid increased disease activity that may be caused by abrupt withdrawal of previous therapy.

Adverse Events

Hypotension may occur during any treatment involving extracorporeal circulation. Closely monitor the patient during the entire treatment for hypotension.
Transient pyretic reactions, 37.7–38.9°C (100–102°F), have been observed in some patients within six to eight hours of reinfusion of the photoactivated leukocyte-enriched blood. A temporary increase in erythroderma may accompany the pyretic reaction.
Treatment frequency exceeding labelling recommendations may result in anaemia.
Venous access carries a small risk of infection and pain.

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOS^TM PHOTOPHERESIS

Consult the 8-methoxypsoralen (Methoxsalen (20 micrograms / mL)) professional leaflet or the oral 8-methoxypsoralen formulation package insert before prescribing or dispensing any medication.

Warnings and Precautions

Patients exhibiting multiple basal cell carcinomas or having a history of basal cell carcinoma should be diligently observed and treated.
Methoxsalen may cause fetal harm when given to a pregnant woman. Women undergoing photopheresis should be advised to avoid becoming pregnant.
Special care should be exercised in treating patients who are receiving concomitant therapy (either topically or systemically) with known photosensitizing agents.
Oral administration of methoxsalen followed by cutaneous UVA exposure (PUVA therapy) is carcinogenic.
Patients should be told emphatically to wear UVA absorbing, wrap-around sunglasses for twenty-four (24) hours after methoxsalen treatment. They should wear these glasses any time they are exposed to direct or indirect sunlight, whether they are outdoors or exposed through a window.

Refer to the package insert for methoxsalen sterile solution (20 micrograms / mL) or the oral 8-methoxypsoralen dosage formulation for a list of all warnings and precautions.

Operators Day UK

Time: 08:15 – 15:00

Brought to you by the Therakos Institute

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IMPORTANT SAFETY INFORMATION FOR THE THERAKOS™ PHOTOPHERESIS PROCEDURE

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOSTM PHOTOPHERESIS

IMPORTANT SAFETY INFORMATION FOR METHOXSALEN USED IN CONJUNCTION WITH THERAKOS^TM PHOTOPHERESIS